
The third week of Prem action gets under way in the East Midlands on Friday when Leicester Tigers host leaders Gloucester for the Slater Cup.
The trophy honours Ed Slater, the former lock who captained both clubs during a playing career that was ended early when he was diagnosed with Motor Neurone Disease (MND) in 2022.
The match comes as a poignant game for both clubs as they raise awareness for charities and causes related to MND.
All the team news for the weekend's five fixtures will land on this page in the coming day.
Once the action begins, you can listen to coverage of all of the matches on BBC DAB and FM local radio, via BBC Sounds or the BBC Sport website and app.
Leicester Tigers v Gloucester (Friday, 19:45 BST)
Hooker Jamie Blamire has been called on to start his first Prem game of the season as Leicester Tigers make five changes to their XV for the visit of Gloucester.
Blamire replaces Samiuela Moli in the front row with Archie van der Flier replacing the hugely experienced Mako Vunipola, who drops to the bench after last week's win at Newcastle Red Bulls.
Finn Carnduff is back in the starting pack, while Ollie Hassell-Collins replaces Adam Radwan on the wing and Will Wand comes in for Solomone Kata, who misses out because of a calf injury.
Meanwhile, Gloucester make two changes to the starting XV that thrashed Harlequins 48-0 last week.
Ben Redshaw replaces George Barton at full-back while and Dian Bleuler moves into the front row instead of Val Rapava-Ruskin.
On the bench, the visitors also have fit-again Wales international Max Llewellyn to call on for the first time this season.
Leicester Tigers: Steward; Hamer-Webb, Wand, Bailey, Hassell-Collins; Searle; Van Poortvliet (c); Van der Flier, Blamire, Heyes; Carnduff, Henderson, Wainwright, Reffell, Cracknell.
Replacements: Moli, Vunipola, Hurd, Thompson, Moro, Whiteley, Woodward, Radwan.
Gloucester: Redshaw; Thorley, Joseph, Atkinson, Loader; Atkinson, Englefield; Bleuler, Lake (c), Fasogbon; Kleyn, Clark, Thomas, Morgan, Trenholm.
Replacements: Innard, Bellamy, Knight, Clement, Ludlow, Robson, Llewellyn, Barton.
Northampton Saints v Bath (Saturday, 15:05 BST)
Team news to appear here.
Saracens v Bristol Bears (Saturday, 17:30 BST)
Team news to appear here.
Exeter Chiefs v Newcastle Red Bulls (Sunday, 15:00 BST)
Team news to appear here.
Sale v Harlequins (Sunday, 15:00 BST)
Team news to appear here.